Hyperbaric Oxygen Therapy for Mild Traumatic Brain Injury Persistent Postconcussion Syndrome and PTSD

Bottom line

Veteran-population HBOT trial supporting state-level TBI/PTSD programmes (OK, TX, FL).

Outcome

Significant improvements in cognitive function, PTSD symptoms, quality of life, depression, and anxiety.

Conditions studied

• Traumatic Brain Injury (TBI) — Multiple RCTs — Moderate evidence, UHMS review pending
• Post-Traumatic Stress Disorder (PTSD) — Early-phase trials — Limited evidence

Full citation

Harch PG, Andrews SR, Fogarty EF, et al. Hyperbaric Oxygen Therapy for Mild Traumatic Brain Injury Persistent Postconcussion Syndrome and PTSD. Medical Gas Research. 2017. doi:10.4103/2045-9912.248263.

View on PubMed (PMID 29204253) →

Related studies

• Hyperbaric Oxygen Therapy Can Improve Post-Concussion Syndrome Years After Mild Traumatic Brain Injury (2013, Level 2)
• Hyperbaric Oxygen May Induce Angiogenesis in Patients with Prolonged Post-Concussion Syndrome (2017, Level 2)
• The Effect of Hyperbaric Oxygen on Symptoms After Mild Traumatic Brain Injury (DoD HOPPS Trial) (2012, Level 1)
• The Hyperoxic-Hypoxic Paradox (2020, Level 5)