Level 1 · RCT / systematic review of RCTs
UHMS-approved
Wound
RCT
Bottom line
The strongest RCT supporting UHMS-approved HBOT for Wagner 3+ diabetic foot ulcers. Supports Medicare coverage criteria.
Outcome
Complete ulcer healing at 1 year: 52% HBOT vs 29% sham. Number needed to treat ≈ 4.
Conditions studied
- Diabetic Wound Healing — Strong (Level 1A) — UHMS approved
Full citation
Löndahl M, Katzman P, Nilsson A, Hammarlund C. Hyperbaric Oxygen Therapy Facilitates Healing of Chronic Foot Ulcers in Patients with Diabetes. Diabetes Care. 2010. doi:10.2337/dc09-1754.
View on PubMed (PMID 20427683) →
Related studies
- Lack of Effectiveness of Hyperbaric Oxygen Therapy for the Treatment of Diabetic Foot Ulcer (2013, Level 3)
- Tenth European Consensus Conference on Hyperbaric Medicine (ECHM) (2017, Level 5)
- Hyperbaric Oxygen Therapy Indications, 15th Edition (UHMS) (2023, Level 5)
- Hyperbaric Oxygen: Its Mechanisms and Efficacy (2011, Level 5)