Level 2 · Prospective cohort / crossover
Neurological
Crossover
Efrati Lab
Bottom line
Supports late-window HBOT (months–years post-stroke) when standard rehabilitation has plateaued.
Outcome
Neurological function + daily-living scores improved; SPECT showed restored metabolism in previously silent regions.
Conditions studied
- Stroke Recovery — Phase 2 RCTs — Moderate evidence
Full citation
Efrati S, Fishlev G, Bechor Y, et al. Hyperbaric Oxygen Induces Late Neuroplasticity in Post-Stroke Patients. PLOS ONE. 2013. doi:10.1371/journal.pone.0053716.
View on PubMed (PMID 23418495) →
Related studies
- The Hyperoxic-Hypoxic Paradox (2020, Level 5)