Level 1 · RCT / systematic review of RCTs
Pediatric
RCT
Controversial
Bottom line
Controversial — supports mild-HBOT for autism but has been challenged on sham-chamber design and effect size.
Outcome
Clinical improvement in receptive language, sensory/cognitive awareness, social interaction at 1.3 ATA.
Conditions studied
- Autism Spectrum (Research) — Mixed — Not currently supported
Full citation
Rossignol DA, Rossignol LW, Smith S, et al. Hyperbaric Treatment for Children with Autism: A Multicenter, Randomized, Double-Blind Controlled Trial. BMC Pediatrics. 2009. doi:10.1186/1471-2431-9-21.