Level 2 · Prospective cohort / crossover
Pain
Crossover
Efrati Lab
Bottom line
First prospective HBOT trial in fibromyalgia; suggests disease-modifying rather than merely symptomatic effect.
Outcome
Significant pain reduction + SPECT-verified reduced brain activity in pain-processing areas.
Conditions studied
- Fibromyalgia — Early RCT — Promising
Full citation
Efrati S, Golan H, Bechor Y, et al. Hyperbaric Oxygen Therapy Can Diminish Fibromyalgia Syndrome — Prospective Clinical Trial. PLOS ONE. 2015. doi:10.1371/journal.pone.0127012.