Level 1 · RCT / systematic review of RCTs
Pediatric
RCT
Methodological debate
Bottom line
Important trial often cited as negative, but 1.3 ATA control arm itself may have been active; interpretation remains contested.
Outcome
Both HBOT and 1.3 ATA "placebo" groups improved similarly on gross motor function — pressure-controlled design limitation.
Full citation
Collet JP, Vanasse M, Marois P, et al. Hyperbaric Oxygen for Children with Cerebral Palsy: A Randomised Multicentre Trial. Lancet. 2001. doi:10.1016/S0140-6736(00)03400-9.