Level 5 · Review / guideline / expert opinion
Safety
Mechanism
Bottom line
Reference for the oxygen-toxicity calculator — defines pressure/time envelope beyond which seizure risk rises steeply.
Outcome
Updated CNS O2 toxicity risk curves — relevant for high-pressure (≥2.8 ATA) and extended-course HBOT.
Conditions studied
- Decompression Sickness — Standard of care — Universal
Full citation
Arieli R. Model of CNS Oxygen Toxicity in Extreme Hyperoxia. Respiratory Physiology & Neurobiology. 2019. doi:10.1016/j.resp.2019.06.012.
View on PubMed (PMID 31255664) →
Related studies
- Treatment of Decompression Illness (2014, Level 5)
- Tenth European Consensus Conference on Hyperbaric Medicine (ECHM) (2017, Level 5)
- Hyperbaric Oxygen Therapy Indications, 15th Edition (UHMS) (2023, Level 5)